Naruto Hashirama Death. Naruto and Hashirama are not even on the same planet in terms of strength. With the blood of the Shodai running through his veins.
Start studying Naruto Characters (in hiragana). What if Naruto received more than just the 'Will of Fire' from Hashirama? But it is highly unlikely that he was assassinated or killed in action.
Hell Hashirama can make a garden of potent flowers to poison Naruto to death if he wants.
The death of Naruto's parents was one of the show's most emotional and vulnerable chapters.
Original image credits to Masashi Kishimoto, Gree Inc. and BANDAI NAMCO Entertainment Inc. Villages did not exist when Hashirama was a child. What if it was something more tangible?